Listed here, we exhibit that conolidine, a pure analgesic alkaloid Utilized in common Chinese medicine, targets ACKR3, thereby offering supplemental proof of a correlation in between ACKR3 and discomfort modulation and opening alternative therapeutic avenues with the treatment of Long-term agony. May possibly assist advertise joint adaptability and mobility: https://www.proleviate.com/post/conolidine-for-pain-relief