The summary that MMPs mediate the breaking down of type II collagen Which aggrecan is ruined by relevant metalloproteinases termed adamalysins with thrombospondin motifs (ADAMTSs) is supported by a considerable body of proof [10]. Fingers: the hands are another common web site for OA. Hand arthritis is characterised by agony, swelling, https://www.theorthopaedicandpainpractice.com/all-you-need-to-know-about-osteoarthritis/