Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716. Our in vitro outcomes suggest that EAM-2201 must be examined concerning prospective in vivo pharmacokinetic drug–drug interactions a result of time-dependent inhibition of CYP2C8, CYP2C9, CYP2C19 and CYP3A4 things to do and competitive inhibition of UGT1A3 exercise. https://eam220120752.webbuzzfeed.com/31656271/details-fiction-and-eam2201