The amide and urea linkage of 54a and 55a facilitated the orientation on the phenyl ring to the solvent, respectively. Further more, indazole group fashioned hydrophobic interactions with HDAC6, While the cap groups occupied the Place exterior the groove. The oxygen atom with the hydroxamic acid group shaped a hydrogen https://franciscofzqfu.blogvivi.com/31653993/the-best-side-of-indazole-ring-formation